Drug Delivery Technology

Penwest has a clear, well-defined growth strategy: to leverage its strength in drug delivery and drug formulation to develop a portfolio of products targeting disorders of the nervous system. The company’s current development pipeline includes products for the treatment of pain, epilepsy, Parkinson's disease, spasticity, and edema. It is continually evaluating new growth opportunities, both internally and externally.

During 2006, Penwest made important progress in pursuit of that strategy. Its key accomplishments included the approval and launch of Opana ER^®by Endo Pharmaceuticals, development of its internal pipeline, and enhancement of its organizational capabilities and processes. For more information, contact Penwest at (845) 878-8400 or visit www.penwest.com.

The Pfeiffer Bidose nasal spray system offers the ideal solution when more medication is required than can be applied via one nostril. The system lends itself for example to the application of pain relief medication and vaccinations. It effectively provides the opportunity to dispense the contained amount of liquid equally into both nasal cavities so that more drug substance can be made available for absorption into the system for a longer period of time. Medication dispensed through the Pfeiffer Bidose system does not come into contact with air prior to being dispensed and therefore remains uncontaminated during the entire shelf-life. Its uniquely consistent spray performance fulfils the need for optimal dispensing efficiency. For more information, visit Pfeiffer of America at www.pfeiffer-group.com.

PharmaCircle is an innovative knowledge management company specializing in the drug delivery, pharmaceutical, and biotechnology fields, with a current client base ranging from start-up life science companies to world leaders in Big Pharma. Clients choose PharmaCircle’s services and content for its comprehensive technical (pipeline, products, molecule, and technology) and business (deals, acquisitions, royalty, licensing, drug revenues, market information, etc) related information and analysis, which are ideal for all segments of small and large companies. PharmaCircle helps facilitate product life cycle management (LCM), partnering, licensing, and competitive intelligence efforts as well as supplements internal efforts and costs at a fraction of the cost if performed internally. For more information, contact PharmaCircle at (847) 729-2960 or visit www.pharmacircle.com.

PharmaForm doesn’t just provide its clients with creative solutions; it creates successful partnerships. As a pharmaceutical contract service provider, it offers a wide range of formulation, drug product development, manufacturing, analytical testing and stability services, patent litigation support services, and product platform licensing opportunities. Its formulation scientists have core expertise and experience in improving solubility of poorly soluble compounds. One such available technique to clients is Evaporative Precipitation into Aqueous Solutions (EPAS), a

process that causes the formation of nano-sized particles that can help enhance bioavailability of a poorly soluble compound. PharmaForm’s state-of-the-art facility is registered with the FDA and the DEA and is cGMP/GLP Compliant. For more information, contact PharmaForm at (512) 834-0449 or visit www.pharmaform.com.